TGF-β1 promotes acinar to ductal metaplasia of human pancreatic acinar cells
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چکیده
منابع مشابه
TGF-β1 promotes acinar to ductal metaplasia of human pancreatic acinar cells
Animal studies suggest that pancreatitis-induced acinar-to-ductal metaplasia (ADM) is a key event for pancreatic ductal adenocarcinoma (PDAC) initiation. However, there has not been an adequate system to explore the mechanisms of human ADM induction. We have developed a flow cytometry-based, high resolution lineage tracing method and 3D culture system to analyse ADM in human cells. In this syst...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2016
ISSN: 2045-2322
DOI: 10.1038/srep30904